Peyronie's disease is an acquired disease of the male reproductive organ. It is caused by excessive production of connective tissue in the penis. This tissue, called scar tissue, can be felt as a lump and is tender. Over time, this tissue causes the penis to lose its elasticity and leads to serious erection problems. Patients usually present with complaints such as shortening of the penis and curvature. The disease is often associated with cardiovascular disease, high blood pressure, diabetes, obesity and smoking. Sixty percent of patients have a cardiovascular risk factor.
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